Desmoglein-2 as a prognostic and biomarker in ovarian cancer
نویسندگان
چکیده
منابع مشابه
FGF18 as a prognostic and therapeutic biomarker in ovarian cancer.
High-throughput genomic technologies have identified biomarkers and potential therapeutic targets for ovarian cancer. Comprehensive functional validation studies of the biological and clinical implications of these biomarkers are needed to advance them toward clinical use. Amplification of chromosomal region 5q31-5q35.3 has been used to predict poor prognosis in patients with advanced stage, hi...
متن کاملGOLPH3L is a Novel Prognostic Biomarker for Epithelial Ovarian Cancer
OBJECTIVE Golgi phosphoprotein 3 (GOLPH3) is a highly conserved membrane protein that is involved in a variety of cancers such as colorectal cancer, gastric cancer, ovarian cancer, and breast cancer. GOLPH3L is a paralog of GOLPH3. Although these proteins share a similar amino acid sequence, much less is known regarding the subcellular functions or effects of GOLPH3L on cancer compared with GOL...
متن کاملTumor Stress-Induced Phosphoprotein1 (STIP1) as a Prognostic Biomarker in Ovarian Cancer
Stress-induced phosphoprotein 1 (STIP1) has been recently identified as a released biomarker in human ovarian cancer. In addition, STIP1 secreted by human ovarian cancer cells has been shown to promote tumor cell proliferation by binding to ALK2 (activin A receptor, type II-like kinase 2) and activating the SMAD-ID3 signaling pathways. In this study, a total of 330 ovarian cancer tumor samples ...
متن کاملCell-free DNA level as a prognostic biomarker for epithelial ovarian cancer.
BACKGROUND The use of cell-free DNA (cfDNA) as a non-invasive biomarker has been evaluated in many types of cancer. This study investigated the prognostic significance of cfDNA level for ovarian cancer. MATERIALS AND METHODS Preoperative sera of 36 patients with ovarian cancer and of 16 with benign tumors were analyzed using commercially available copy number assay kits to measure the cfDNA l...
متن کاملDiminished miR-613 expression as a novel prognostic biomarker for human ovarian cancer.
OBJECTIVE miR-613 may suppress ovarian cancer development and progression. We wished to assess the potential prognostic value of miR-613 expression analysis in ovarian cancer. PATIENTS AND METHODS A total of 236 pairs of human ovarian cancer and matched normal tissue specimens were collected. Resected tissue specimens were obtained during the operation and were snap-frozen in liquid nitrogen ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2020
ISSN: 1538-4047,1555-8576
DOI: 10.1080/15384047.2020.1843323